Description

5-(4-Fluoro-Phenyl)-Isoxazole-3-Carboxylic Acid is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical precursor for developing novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the creation of molecules with enhanced biological activity. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, leveraging the bioactivity of the isoxazole and fluorophenyl motifs.
• Chemical Biology Probe: Serves as a scaffold for designing enzyme inhibitors and molecular probes to study biological pathways.
• Material Science Precursor: Potential building block for advanced polymers and liquid crystals due to its rigid, aromatic structure.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and process development projects.

Basic Information

Product Name	5-(4-Fluoro-Phenyl)-Isoxazole-3-Carboxylic Acid
CAS No.	33282-24-5
Molecular Formula	C10H6FNO3
Molecular Weight	207.16 g/mol
Synonyms	5-(4-Fluorophenyl)isoxazole-3-carboxylic acid; 3-Isoxazolecarboxylic acid, 5-(4-fluorophenyl)-; 4-Fluoro-5-phenylisoxazole-3-carboxylic acid; 5-(p-Fluorophenyl)-3-isoxazolecarboxylic acid; 33282-24-5; 5-(4-Fluorophenyl)-1,2-oxazole-3-carboxylic acid; 5-(4-Fluorophenyl)isoxazol-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(4-Fluoro-Phenyl)-Isoxazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with complete batch data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.