Description

6-Nitronicotinic Acid is a high-purity, versatile nitropyridine derivative essential for advanced chemical synthesis. This compound serves as a critical building block in the development of complex molecules, offering a reactive nitro group and a carboxylic acid functionality for diverse coupling and derivatization reactions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal catalysis and coordination chemistry.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development-scale batches.

Basic Information

Product Name	6-Nitronicotinic Acid
CAS No.	33225-73-9
Molecular Formula	C6H4N2O4
Molecular Weight	168.11 g/mol
Synonyms	6-Nitropyridine-3-carboxylic Acid; 3-Carboxy-6-nitropyridine; 5-Nitro-3-pyridinecarboxylic Acid; Nicotinic Acid, 6-Nitro-; 6-Nitro-3-pyridinecarboxylic Acid; 6-Nitronicotinate; 6-Nitro-3-carboxypyridine
EINECS	Contact for details

Quality Control

Our 6-Nitronicotinic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation via FT-IR and NMR, and residual solvent analysis. A Certificate of Analysis (COA) is supplied with every batch, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	245 - 250 °C (dec.)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.