Description

7-Chloro-2-Mercaptoquinazolin-4(3H)-One is a versatile heterocyclic building block and key synthetic intermediate. This compound matters for its role as a crucial precursor in the development of pharmacologically active molecules, particularly in medicinal chemistry. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for synthesizing potential drug candidates, especially those targeting central nervous system disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of quinazolinone-based drug candidates with potential CNS activity.
• Medicinal Chemistry Research: Used in the discovery and development of novel therapeutic agents, including kinase inhibitors and receptor modulators.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides.
• Dye and Pigment Manufacturing: Utilized in the synthesis of specialized heterocyclic dyes and colorants.
• Material Science: Investigated as a monomer or additive for creating advanced polymeric materials with specific properties.
• Chemical Biology Probes: Employed in the design of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	7-Chloro-2-Mercaptoquinazolin-4(3H)-One
CAS No.	33017-86-6
Molecular Formula	C8H5ClN2OS
Molecular Weight	212.66 g/mol
Synonyms	7-Chloro-4-hydroxy-2-mercaptoquinazoline; 7-Chloro-2-mercapto-3,4-dihydro-4-oxoquinazoline; 7-Chloro-2-sulfanyl-3H-quinazolin-4-one; 4(3H)-Quinazolinone, 7-chloro-2-mercapto-; 2-Mercapto-7-chloro-4(3H)-quinazolinone; 7-Chloro-2-thioxo-1,2-dihydro-4H-quinazolin-4-one; 7-Chloro-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
EINECS	Contact for details

Quality Control

Our 7-Chloro-2-Mercaptoquinazolin-4(3H)-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.