Description

α-D-Glucose-1-Phosphate Disodium Salt Tetrahydrate is a high-purity biochemical reagent and a key phosphorylated sugar intermediate. This compound is essential for enzymatic studies and metabolic pathway research, offering a defined substrate for kinases and other enzymes. It is primarily required by research institutions, diagnostic kit manufacturers, and biotechnology companies working in carbohydrate metabolism, enzymology, and molecular biology.

Application

• Enzymatic Research Substrate: Used as a specific substrate for enzymes like phosphoglucomutase and UDP-glucose pyrophosphorylase in kinetic and mechanistic studies.
• Biochemical Assay Standard: Serves as a critical standard or reagent in diagnostic kits and in vitro assays for measuring enzyme activities related to glycogen and glucose metabolism.
• Metabolic Pathway Studies: Employed in research on glycolysis, gluconeogenesis, and carbohydrate biosynthesis to trace and understand metabolic fluxes.
• Pharmaceutical Intermediate: Acts as a potential starting material or intermediate in the synthesis of more complex bioactive molecules and prodrugs.
• Cell Culture & Microbiology: Utilized in defined microbial media and cell culture systems to study energy metabolism and sugar phosphate utilization.

Basic Information

Product Name	α-D-Glucose-1-Phosphate Disodium Salt Tetrahydrate
CAS No.	32972-46-6
Molecular Formula	C6H11Na2O9P · 4H2O
Molecular Weight	376.15 g/mol (anhydrous basis)
Synonyms	D-Glucose 1-phosphate disodium salt tetrahydrate; Cori Ester Disodium Salt Tetrahydrate; α-D-Glucopyranose 1-phosphate disodium salt tetrahydrate; 1-O-Phosphono-α-D-glucopyranose disodium salt tetrahydrate; G-1-P Disodium Salt; Glucose-1-P Na2; α-D-Glucose-1-phosphate disodium salt
EINECS	Contact for details

Quality Control

Our α-D-Glucose-1-Phosphate Disodium Salt Tetrahydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container should be opened under a dry atmosphere and resealed immediately after use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	16.0% - 19.0% (Theoretical for Tetrahydrate: ~19.2%)
pH (5% solution)	7.0 - 9.0
Specific Rotation [α]20/D	+75° to +85° (c=1 in water)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.