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1-Bromo-6-(Trimethylammonium)Hexyl Bromide CAS NO 32765-81-4


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CAS No.:32765-81-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Bromo-6-(Trimethylammonium)Hexyl Bromide is a versatile bifunctional alkylating agent featuring both a reactive bromoalkyl chain and a permanently charged quaternary ammonium group. This unique structure makes it a critical intermediate for introducing cationic functionality and cross-linking capabilities into target molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise molecular modification and polymer synthesis.

Application

  • Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating cationic prodrugs or agents that modify cellular uptake.
  • Bioconjugation & Protein Modification: Acts as a linker or cross-linking agent for attaching functional groups or labels to proteins, antibodies, and other biomolecules.
  • Polymer & Dendrimer Synthesis: Serves as a key monomer or branching unit in the production of cationic polymers, dendrimers, and hydrogels for drug delivery systems.
  • Surface Functionalization: Used to create permanent cationic charges on surfaces of materials, membranes, or nanoparticles to alter their interaction properties.
  • Quaternary Ammonium Compound (QAC) Precursor: A building block for synthesizing specialized QACs with extended alkyl chains for research in antimicrobials or surfactants.
  • Gene Delivery Research: Investigated as a component for constructing non-viral vectors, such as lipopolyplexes, to enhance DNA/RNA complexation and cellular transfection.
  • Material Science: Employed in the development of ion-exchange resins, conductive polymers, and smart materials requiring fixed positive charges.

Basic Information

Product Name 1-Bromo-6-(Trimethylammonium)Hexyl Bromide
CAS No. 32765-81-4
Molecular Formula C9H21Br2N
Molecular Weight 311.08 g/mol
Synonyms 6-Bromohexyltrimethylammonium Bromide; N,N,N-Trimethyl-6-bromo-1-hexanaminium Bromide; Hexamethylene-1,6-bis(trimethylammonium bromide) derivative; 1,6-Dibromohexane bis(trimethylammonium) salt (related); Bromohexyltrimethylammonium Bromide; (6-Bromohexyl)trimethylammonium Bromide; TMAB-Hex-Br; Cationic Hexyl Bromide
EINECS Contact for details

Quality Control

Every batch of 1-Bromo-6-(Trimethylammonium)Hexyl Bromide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and reducing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Melting Point Contact for details
Heavy Metals < 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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