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1-Bromo-6-(Trimethylammonium)Hexyl Bromide CAS NO 32765-81-4
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CAS No.:32765-81-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-Bromo-6-(Trimethylammonium)Hexyl Bromide is a versatile bifunctional alkylating agent featuring both a reactive bromoalkyl chain and a permanently charged quaternary ammonium group. This unique structure makes it a critical intermediate for introducing cationic functionality and cross-linking capabilities into target molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise molecular modification and polymer synthesis.
Application
- Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating cationic prodrugs or agents that modify cellular uptake.
- Bioconjugation & Protein Modification: Acts as a linker or cross-linking agent for attaching functional groups or labels to proteins, antibodies, and other biomolecules.
- Polymer & Dendrimer Synthesis: Serves as a key monomer or branching unit in the production of cationic polymers, dendrimers, and hydrogels for drug delivery systems.
- Surface Functionalization: Used to create permanent cationic charges on surfaces of materials, membranes, or nanoparticles to alter their interaction properties.
- Quaternary Ammonium Compound (QAC) Precursor: A building block for synthesizing specialized QACs with extended alkyl chains for research in antimicrobials or surfactants.
- Gene Delivery Research: Investigated as a component for constructing non-viral vectors, such as lipopolyplexes, to enhance DNA/RNA complexation and cellular transfection.
- Material Science: Employed in the development of ion-exchange resins, conductive polymers, and smart materials requiring fixed positive charges.
Basic Information
| Product Name | 1-Bromo-6-(Trimethylammonium)Hexyl Bromide |
| CAS No. | 32765-81-4 |
| Molecular Formula | C9H21Br2N |
| Molecular Weight | 311.08 g/mol |
| Synonyms | 6-Bromohexyltrimethylammonium Bromide; N,N,N-Trimethyl-6-bromo-1-hexanaminium Bromide; Hexamethylene-1,6-bis(trimethylammonium bromide) derivative; 1,6-Dibromohexane bis(trimethylammonium) salt (related); Bromohexyltrimethylammonium Bromide; (6-Bromohexyl)trimethylammonium Bromide; TMAB-Hex-Br; Cationic Hexyl Bromide |
| EINECS | Contact for details |
Quality Control
Every batch of 1-Bromo-6-(Trimethylammonium)Hexyl Bromide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and reducing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder or solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 1.0% |
| Melting Point | Contact for details |
| Heavy Metals | < 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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