Description

1',2'-Dihydro-Spiro[Cyclobutane-1,3'-[3H]Indole] is a high-value spirocyclic organic compound featuring a unique fused indole-cyclobutane structure. This molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Scaffold: Used extensively in hit-to-lead and lead optimization programs to explore structure-activity relationships (SAR) due to its rigid, three-dimensional spiro framework.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Organic Synthesis Reagent: Acts as a specialized precursor or reactant in complex organic transformations, including cycloadditions and cross-coupling reactions.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Material Science Research: Investigated as a monomer or precursor for creating novel organic electronic materials or polymers with specific optical properties.

Basic Information

Product Name	1',2'-Dihydro-Spiro[Cyclobutane-1,3'-[3H]Indole]
CAS No.	32670-02-3
Molecular Formula	C11H11N
Molecular Weight	157.21 g/mol
Synonyms	Spiro[cyclobutane-1,3'-indole], 1',2'-Dihydro-; 1'H-Spiro[cyclobutane-1,3'-indole]; 1',2'-Dihydrospiro[cyclobutane-1,3'-indole]; 2,3-Dihydro-1H-spiro[indole-3,1'-cyclobutane]; 32670-02-3; Spiro[indole-3,1'-cyclobutane], 1,2-dihydro-; Spiro[cyclobutane-1,3'-indoline]
EINECS	Contact for details

Quality Control

Our 1',2'-Dihydro-Spiro[Cyclobutane-1,3'-[3H]Indole] is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.