Description

(S)-2,2'-Dimethyl-1,1'-Binaphthyl is a high-purity, chiral binaphthyl derivative widely used as a privileged ligand and building block in asymmetric synthesis. Its value lies in its ability to impart significant stereochemical control in catalytic reactions, enabling the production of enantiomerically pure compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require high-performance chiral auxiliaries for process development and scale-up.

Application

• As a chiral ligand in transition metal catalysis (e.g., for asymmetric hydrogenation, C-C bond formation).
• As a core scaffold for constructing chiral organocatalysts and phase-transfer catalysts.
• In the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and agrochemical intermediates.
• As a resolving agent for the separation of chiral compounds.
• In the development of chiral stationary phases for analytical and preparative chromatography.
• As a building block for chiral polymers and functional materials with optical properties.
• For fundamental academic research in stereochemistry and asymmetric synthesis methodologies.

Basic Information

Product Name	(S)-2,2'-Dimethyl-1,1'-Binaphthyl
CAS No.	32587-64-7
Molecular Formula	C22H18
Molecular Weight	282.38 g/mol
Synonyms	(S)-2,2'-Dimethyl-1,1'-binaphthalene; (S)-2,2'-Dimethylbinaphthyl; (S)-DM-BINAP (precursor); (S)-1,1'-Bi-2-naphthol dimethyl ether derivative; (S)-2,2'-Dimethyl-[1,1'-binaphthalene]; (S)-BINOL dimethyl ether; (S)-2,2'-Dimethyl-1,1'-binaphthyl; (S)-2,2'-Dimethyl-1,1'-dinaphthyl
EINECS	Contact for details

Quality Control

Our (S)-2,2'-Dimethyl-1,1'-Binaphthyl is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and GC/HPLC for chemical purity. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific customer requirements for research or cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.