Description

D-Glucurone is a vital cyclic form of D-glucuronic acid, serving as a key intermediate and precursor in numerous biochemical and industrial synthesis pathways. Its primary commercial value lies in its role as a versatile building block for producing glucuronides, which are essential for detoxification processes, drug metabolism studies, and the synthesis of bioactive compounds. This high-purity chemical is critically needed by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in developing therapeutic agents, diagnostic tools, and advanced biomaterials.

Application

• Pharmaceutical Intermediate: Crucial for the synthesis of glucuronide metabolites used in drug development, pharmacokinetic studies, and prodrug design.
• Biochemical Research: Employed as a substrate or standard in enzymatic assays, metabolic pathway analysis, and studies of glucuronidation processes.
• Diagnostic Reagent Manufacturing: Used in the production of reagents for clinical diagnostics that measure glucuronidase or glucuronyltransferase activity.
• Fine Chemical Synthesis: Acts as a chiral starting material for the synthesis of complex carbohydrates, glycosides, and other specialty organic compounds.
• Cosmetic & Personal Care: Potential application in the development of skin-active ingredients that leverage glucuronic acid's hydrating and renewing properties.
• Nutritional & Dietary Supplements: Investigated for use in advanced supplement formulations targeting detoxification support and liver health.

Basic Information

Product Name	D-Glucurone
CAS No.	32449-92-6
Molecular Formula	C6H8O6
Molecular Weight	176.12 g/mol
Synonyms	D-Glucuronolactone; Glucuronic acid γ-lactone; D-Glucurono-3,6-lactone; D-Glucurono-6,3-lactone; Glucuronolactone; Glucurolactone; Glucurone; (3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-one
EINECS	251-053-3

Quality Control

Our D-Glucurone is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide material that meets rigorous in-house specifications, with typical purity levels exceeding 98% (HPLC). A comprehensive Certificate of Analysis (COA) detailing identity, purity, residual solvents, and related substances is supplied with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Specific Rotation	+19.0° to +21.0° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.