Description

3-Thiophenecarboxylicacid,5-Fluoro-(8Ci,9Ci) is a high-purity fluorinated heterocyclic building block, specifically a 5-fluorothiophene-3-carboxylic acid derivative. This compound is valued for its role as a critical synthon in advanced organic synthesis, enabling the introduction of both a carboxylic acid handle and a fluorine-substituted thiophene moiety. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by material scientists developing specialty polymers and electronic materials. The CAS number for this product is 32415-50-2.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom and thiophene ring enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: The carboxylic acid group allows for coordination to metals, making it useful for creating novel ligands in catalytic systems.
• Fluorine Chemistry Studies: An important reagent for investigating structure-activity relationships (SAR) and the effects of fluorine substitution in heterocyclic systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific custom synthesis projects.

Basic Information

Item	Detail
Product Name	3-Thiophenecarboxylicacid,5-Fluoro-(8Ci,9Ci)
CAS No.	32415-50-2
Molecular Formula	C5H3FO2S
Molecular Weight	146.14 g/mol
Synonyms	5-Fluorothiophene-3-carboxylic acid; 5-Fluoro-3-thiophenecarboxylic acid; 3-Carboxy-5-fluorothiophene; 5-Fluoro-thiophene-3-carboxylic acid; 5-Fluorothiophene-3-carboxylicacid; 32415-50-2; 5-Fluoro-3-thiophene carboxylic acid; 5-Fluorothiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 3-Thiophenecarboxylicacid,5-Fluoro-(8Ci,9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and other relevant analytical techniques, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under a dry inert atmosphere for long-term storage and to minimize exposure to moisture. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.