Description

1,2-o-Isopropylidene-A-D-Glucofuranose is a protected sugar derivative, a crucial chiral building block in organic synthesis. Its primary value lies in providing a stable, non-reactive scaffold for the selective functionalization of carbohydrate molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for the synthesis of nucleosides, antiviral agents, and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of nucleoside analogs and antiviral drugs.
• Chiral Building Block: Used in asymmetric synthesis to introduce carbohydrate-based chirality into complex molecules.
• Glycochemistry Research: Serves as a protected precursor for the preparation of more complex sugars and glycoconjugates.
• Agrochemical Synthesis: Intermediate in the production of certain herbicides and plant growth regulators with specific stereochemistry.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring precise stereocontrol.
• Biochemical Tool: Used in enzymatic studies and the development of carbohydrate-based probes and inhibitors.

Basic Information

Item	Detail
Product Name	1,2-o-Isopropylidene-A-D-Glucofuranose
CAS No.	32365-83-6
Molecular Formula	C9H16O6
Molecular Weight	220.22 g/mol
Synonyms	1,2-O-Isopropylidene-α-D-glucofuranose; 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose (common misnomer, often used interchangeably); α-D-Glucofuranose, 1,2-O-(1-methylethylidene)-; Isopropylidene glucose; D-Glucose isopropylidene acetal; Acetone glucose; 1,2-O-(1-Methylethylidene)-α-D-glucofuranose
EINECS	251-011-1

Quality Control

Our 1,2-o-Isopropylidene-A-D-Glucofuranose is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, optical rotation for chiral identity, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-19.0° to -21.0° (c=1 in H₂O)
Melting Point	159°C - 163°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.