Description

(R)-4-Bromomandelic Acid is a high-purity chiral building block and resolving agent of significant importance in asymmetric synthesis. Its value lies in its utility for introducing the mandelic acid pharmacophore and for the optical resolution of racemic amines and alcohols. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and other enantiomerically pure substances.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key building block for the production of enantiomerically pure drugs, especially those containing the mandelic acid scaffold.
• Optical Resolution Agent: Used to separate racemic mixtures of amines, amino acids, and other chiral compounds via diastereomeric salt formation.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in metal-catalyzed asymmetric reactions.
• Agrochemical Intermediate: Employed in the research and development of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Specialty Chemical Production: Used in the synthesis of complex molecules for advanced materials and electronics.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic and medicinal chemistry.

Basic Information

Item	Details
Product Name	(R)-4-Bromomandelic Acid
CAS No.	32189-34-7
Molecular Formula	C8H7BrO3
Molecular Weight	231.04 g/mol
Synonyms	(R)-(-)-4-Bromomandelic Acid; (R)-4-Bromophenylglycolic Acid; (R)-α-Hydroxy-4-bromobenzeneacetic Acid; (2R)-2-Hydroxy-2-(4-bromophenyl)acetic Acid; D-(-)-4-Bromomandelic Acid; (R)-O-Bromomandelic Acid; p-Bromomandelic Acid (R-enantiomer)
EINECS	Contact for details

Quality Control

Our (R)-4-Bromomandelic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Melting Point	158°C - 162°C
Loss on Drying	≤0.5%
Residue on Ignition (Sulfated Ash)	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.