Description

4-Chloro-3-Fluorobenzotrifluoride is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents on a trifluoromethylated benzene ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop new active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a core component in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronics: Employed in the synthesis of semiconductors and charge-transport materials for OLEDs and other electronic devices.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorine into polymers, enhancing their chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and creating novel fluorinated compounds in academic and industrial R&D labs.

Basic Information

Product Name	4-Chloro-3-Fluorobenzotrifluoride
CAS No.	32137-20-5
Molecular Formula	C7H3ClF4
Molecular Weight	198.55 g/mol
Synonyms	1-Chloro-2-fluoro-4-(trifluoromethyl)benzene; 4-Chloro-3-fluoro-α,α,α-trifluorotoluene; 3-Fluoro-4-chlorobenzotrifluoride; 4-Chloro-α,α,α-trifluoro-3-fluorotoluene; 2-Fluoro-4-(trifluoromethyl)chlorobenzene; 4-Chloro-3-fluoro-1-(trifluoromethyl)benzene; 4-Chloro-3-fluorobenzylidyne trifluoride
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluorobenzotrifluoride is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from strong acids and organic solvents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	≤ 2.0% (Total)
Density (at 20°C)	~1.48 g/mL
Refractive Index (n20D)	~1.42

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.