Description

2-Chloro-5-[2-(Dimethylamino)Ethyl]-11-Phenyl-5H-Dibenzo[B,E][1,4]Diazepine is a high-purity, specialized dibenzodiazepine derivative of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for research into novel bioactive molecules. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel psychotropic and central nervous system (CNS) active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new drug candidates targeting specific receptors.
• Biochemical Tool Compound: Employed in pharmacological research to study receptor binding and signal transduction pathways.
• Fine Chemical Synthesis: Serves as a sophisticated building block for creating complex, high-value specialty chemicals with specific functionalities.
• Reference Standard: Supplied as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	2-Chloro-5-[2-(Dimethylamino)Ethyl]-11-Phenyl-5H-Dibenzo[B,E][1,4]Diazepine
CAS No.	32047-66-8
Molecular Formula	C25H24ClN3
Molecular Weight	401.93 g/mol
Synonyms	2-Chloro-11-phenyl-5-[2-(dimethylamino)ethyl]-5H-dibenzo[b,e][1,4]diazepine; Loxapine Impurity; Loxapine Related Compound; 5H-Dibenzo[b,e][1,4]diazepine, 2-chloro-5-[2-(dimethylamino)ethyl]-11-phenyl-; Loxapine EP Impurity C; Loxapine USP Related Compound C
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-[2-(Dimethylamino)Ethyl]-11-Phenyl-5H-Dibenzo[B,E][1,4]Diazepine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Production can be aligned with cGMP guidelines for pharmaceutical intermediate applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.