Description

2-Acetylamino-1-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-2-Deoxy-D-Glucopyranose is a key protected monosaccharide derivative, extensively utilized as a sophisticated synthetic intermediate in advanced organic chemistry. Its fully silylated and acetylated structure provides exceptional stability and solubility, enabling precise, high-yield glycosylation reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors, particularly for the synthesis of complex oligosaccharides, glycoconjugates, and novel active pharmaceutical ingredients (APIs).

Application

• Glycosylation Reagent: A critical building block for the stereoselective synthesis of complex oligosaccharides and glycans.
• Pharmaceutical Intermediate: Used in the research and development of carbohydrate-based drugs, antiviral agents, and antibiotics.
• Glycoconjugate Synthesis: Facilitates the creation of glycoproteins, glycolipids, and other biologically active conjugates for biochemical studies.
• Carbohydrate Chemistry Research: Serves as a protected precursor for exploring novel synthetic pathways and developing new glycosylation methodologies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, chiral auxiliaries, and advanced material precursors.
• Standards and Reference Materials: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Acetylamino-1-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-2-Deoxy-D-Glucopyranose
CAS No.	31980-72-0
Molecular Formula	C20H47NO6Si4
Molecular Weight	534.0 g/mol
Synonyms	2-Acetamido-1,3,4,6-tetra-O-trimethylsilyl-2-deoxy-D-glucopyranose; 2-Deoxy-2-acetamido-1,3,4,6-tetra-O-trimethylsilyl-D-glucopyranose; N-Acetyl-1,3,4,6-tetra-O-trimethylsilyl-2-amino-2-deoxy-D-glucopyranose; Per-O-trimethylsilylated N-Acetylglucosamine; GlcNAc(1,3,4,6-OTMS)2-NHAc; TMS-protected N-Acetyl-D-glucosamine; 1,3,4,6-Tetra-O-trimethylsilyl-N-acetyl-D-glucosamine
EINECS	Contact for details

Quality Control

Our 2-Acetylamino-1-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-2-Deoxy-D-Glucopyranose is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.