Description

1-Bromo-2-Methoxy-3-Nitro-Benzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex aromatic and heterocyclic systems.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the nitro and bromo groups serve as handles for further functionalization.
• Dye and Pigment Manufacturing: Serves as a starting material for the production of specialized azo dyes and other colorants.
• Material Science Research: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination, enabling carbon-carbon and carbon-heteroatom bond formation.
• Ligand and Catalyst Development: Used to synthesize novel chelating ligands for metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	1-Bromo-2-Methoxy-3-Nitro-Benzene
CAS No.	31872-76-1
Molecular Formula	C7H6BrNO3
Molecular Weight	232.03 g/mol
Synonyms	2-Bromo-6-Nitroanisole; 3-Nitro-2-Bromoanisole; 1-Bromo-2-Methoxy-3-Nitrobenzene; 2-Methoxy-6-Nitrobromobenzene; Benzene, 1-bromo-2-methoxy-3-nitro-; o-Bromo-m-nitroanisole
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Methoxy-3-Nitro-Benzene is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing purity, identity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.