Description

trans-(1R,2R)-2-Aminocyclopentanol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. Its defined stereochemistry is critical for the development of enantiomerically pure compounds, particularly in medicinal chemistry and asymmetric synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable source of a specific stereoisomer for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for transition metal catalysis.
• Agrochemical Research: Serves as a building block for creating novel, enantiopure pesticides and herbicides.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and specialty chemicals where stereocontrol is paramount.
• Bioconjugation & Probe Development: The amino and hydroxyl functional groups make it suitable for modifying biomolecules or creating molecular probes for biochemical research.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Item	Detail
Product Name	trans-(1R,2R)-2-Aminocyclopentanol Hydrochloride
CAS No.	31775-67-4
Molecular Formula	C5H12ClNO
Molecular Weight	137.61 g/mol
Synonyms	(1R,2R)-2-Aminocyclopentanol Hydrochloride; (1R,2R)-2-Amino-1-cyclopentanol Hydrochloride; trans-2-Aminocyclopentanol Hydrochloride (1R,2R)-; (1R,2R)-1-Amino-2-hydroxycyclopentane Hydrochloride; (1R,2R)-2-Amino-cyclopentan-1-ol Hydrochloride; (1R,2R)-2-Aminocyclopentyl Alcohol Hydrochloride; Aminocyclopentanol HCl, trans-(1R,2R)-
EINECS	Contact for details

Quality Control

Our trans-(1R,2R)-2-Aminocyclopentanol Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.