Description

8-(Trifluoromethyl)Quinoline-3-Carboxylic Acid is a high-value, multifunctional heterocyclic building block prized for its unique trifluoromethyl-substituted quinoline scaffold. This compound is essential for introducing both lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used to create novel active ingredients for crop protection products, leveraging the bioactivity of the quinoline core.
• Material Science Research: Serves as a building block for organic semiconductors, ligands for catalysis, and specialty polymers.
• Chemical Synthesis: Versatile intermediate for further functionalization, enabling the creation of complex molecular libraries for screening.
• Fluorine Chemistry Studies: Ideal substrate for investigating the effects of the trifluoromethyl group on chemical and physical properties.

Basic Information

Product Name	8-(Trifluoromethyl)Quinoline-3-Carboxylic Acid
CAS No.	31588-79-1
Molecular Formula	C11H6F3NO2
Molecular Weight	241.17 g/mol
Synonyms	3-Quinolinecarboxylic acid, 8-(trifluoromethyl)-; 8-Trifluoromethylquinoline-3-carboxylic acid; 8-(Trifluoromethyl)-3-quinolinecarboxylic acid; Quinoline-3-carboxylic acid, 8-(trifluoromethyl)-; 31588-79-1; 8-CF3-Quinoline-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethyl)Quinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.