Description

2-(Benzyloxy)Bromobenzene is a versatile aryl benzyl ether derivative featuring a bromine substituent, making it a valuable bifunctional intermediate in advanced organic synthesis. Its molecular structure provides two distinct reactive sites, enabling its use in the construction of complex pharmaceutical scaffolds and specialty chemicals. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for building block applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring diaryl ether or benzyl-protected phenol motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides where the bromobenzene moiety is utilized for further functionalization.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized phosphine or nitrogen-based ligands used in transition metal catalysis.
• Material Science Research: Employed in the development of organic electronic materials, such as hole-transporting materials or monomers for conjugated polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions like Suzuki, Heck, or Buchwald-Hartwig amination.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and constructing molecular libraries for screening.

Basic Information

Item	Details
Product Name	2-(Benzyloxy)Bromobenzene
CAS No.	31575-75-4
Molecular Formula	C₁₃H₁₁BrO
Molecular Weight	263.13 g/mol
Synonyms	1-Bromo-2-(benzyloxy)benzene; o-(Benzyloxy)bromobenzene; 2-Bromophenyl benzyl ether; Benzyl 2-bromophenyl ether; Bromobenzene, 2-(benzyloxy)-; (2-Bromophenoxy)methyl]benzene
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)Bromobenzene is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the consistency and reliability required for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.