Description

(2S)-3,3-Dimethylbutan-2-Amine Hydrochloride is a high-purity chiral amine salt of significant interest in advanced organic synthesis. This compound matters as a crucial chiral building block and resolving agent for the preparation of enantiomerically pure pharmaceuticals and fine chemicals. It is needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and other therapeutics requiring high stereochemical purity.
• Chiral Resolving Agent: Used for the separation of racemic mixtures of carboxylic acids and other compounds via diastereomeric salt formation.
• Asymmetric Synthesis Catalyst/ Ligand Precursor: Serves as a precursor for chiral ligands or catalysts used in enantioselective transformations.
• Agrochemical Research: Employed in the development of chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	(2S)-3,3-Dimethylbutan-2-Amine Hydrochloride
CAS No.	31519-55-8
Molecular Formula	C6H15N•HCl
Molecular Weight	137.65 g/mol (Free base: 101.19 g/mol)
Synonyms	(S)-3,3-Dimethyl-2-butanamine hydrochloride; (S)-tert-Butylmethylamine hydrochloride; (S)-1,1-Dimethyl-2-methylpropylamine hydrochloride; (2S)-3,3-Dimethylbutan-2-aminium chloride; L-tert-Butylmethylamine HCl; (S)-(-)-tert-Butylmethylamine hydrochloride; (S)-2-Amino-3,3-dimethylbutane hydrochloride; (S)-1-Amino-2,2-dimethylpropane hydrochloride
EINECS	Contact for details

Quality Control

Our (2S)-3,3-Dimethylbutan-2-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets exacting standards for research and production. Certificates of Analysis (COA) with full analytical data are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Enantiomeric Excess)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition (Sulfated Ash)	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.