Description

(2R)-3,3-Dimethylbutan-2-Amine Hydrochloride is a high-purity chiral amine salt, a critical building block in advanced organic synthesis. Its value lies in its role as a key chiral intermediate for the development of active pharmaceutical ingredients (APIs) and specialty chemicals, where stereochemical purity is paramount. This compound is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, particularly for entities requiring enantiomerically pure intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry affects biological activity.
• Catalyst Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis.
• Fine Chemical Manufacturing: Employed in the synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Industrial Research: A valuable reagent for method development and exploration of new synthetic pathways in organic chemistry.

Basic Information

Product Name	(2R)-3,3-Dimethylbutan-2-Amine Hydrochloride
CAS No.	31519-54-7
Molecular Formula	C6H15N•HCl
Molecular Weight	137.65 g/mol (Free base: 101.19 g/mol)
Synonyms	(R)-3,3-Dimethyl-2-butanamine hydrochloride; (R)-tert-Butylmethylamine hydrochloride; (2R)-3,3-Dimethylbutan-2-aminium chloride; (R)-1,1-Dimethyl-2-methylpropylamine hydrochloride; (R)-2-Amino-3,3-dimethylbutane hydrochloride; (R)-t-Butylmethylamine HCl; (R)-N-Methyl-tert-butylamine hydrochloride; (R)-1,1-Dimethyl-2-aminopropane hydrochloride
EINECS	Contact for details

Quality Control

Our (2R)-3,3-Dimethylbutan-2-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.