Description

(S)-3-Methylbutan-2-Amine Hydrochloride CAS NO 31519-53-6 is a high-purity chiral amine salt, a key building block in asymmetric synthesis. Its value lies in providing a defined stereocenter for the production of enantiomerically pure pharmaceuticals and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, fine chemical, and agrochemical industries who require a reliable source of a specific enantiomer for chiral intermediate synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for chiral herbicides, fungicides, and pesticides, where the specific stereochemistry can impact biological activity and environmental profile.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs exploring structure-activity relationships (SAR).

Basic Information

Product Name	(S)-3-Methylbutan-2-Amine Hydrochloride
CAS No.	31519-53-6
Molecular Formula	C5H14ClN
Molecular Weight	123.62 g/mol
Synonyms	(S)-2-Amino-3-methylbutane hydrochloride; (S)-1,2-Dimethylpropylamine hydrochloride; (S)-sec-Isoamylamine hydrochloride; (S)-3-Methyl-2-butylamine hydrochloride; L-sec-Isoamylamine hydrochloride; (2S)-3-Methylbutan-2-amine hydrochloride; (S)-(-)-1,2-Dimethylpropylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-3-Methylbutan-2-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.