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4,7-Dichloro-2-[(1E,3E)-4-(5-Nitro-2-Furyl)Buta-1,3-Dienyl]Quinoline CAS NO 31432-69-6


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CAS No.:31432-69-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4,7-Dichloro-2-[(1E,3E)-4-(5-Nitro-2-Furyl)Buta-1,3-Dienyl]Quinoline is a specialized heterocyclic compound that serves as a high-value synthetic intermediate and research chemical. Its unique molecular architecture, featuring a quinoline core linked to a nitro-substituted furan via a conjugated diene bridge, makes it a critical precursor for developing novel pharmacologically active agents. This compound is primarily sought by research institutions and pharmaceutical developers focused on medicinal chemistry, particularly in the synthesis of potential anti-infective and anticancer candidates.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of novel quinoline-based drug candidates for therapeutic research.
  • Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies targeting various biological pathways.
  • Anti-infective Agent Development: Serves as a precursor for compounds being investigated for antibacterial and antiparasitic properties.
  • Chemical Biology Probes: Utilized in the development of fluorescent or bioactive probes for studying cellular processes.
  • Organic Synthesis: Valuable intermediate in complex multi-step organic syntheses due to its reactive functional groups.
  • Material Science Research: Potential precursor for organic electronic materials due to its extended conjugated pi-system.

Basic Information

Product Name 4,7-Dichloro-2-[(1E,3E)-4-(5-Nitro-2-Furyl)Buta-1,3-Dienyl]Quinoline
CAS No. 31432-69-6
Molecular Formula C₁₇H₁₀Cl₂N₂O₃
Molecular Weight 361.18 g/mol
Synonyms 2-[(1E,3E)-4-(5-Nitro-2-furanyl)-1,3-butadien-1-yl]-4,7-dichloroquinoline; 4,7-Dichloro-2-[4-(5-nitro-2-furyl)-1,3-butadienyl]quinoline; 4,7-Dichloro-2-[4-(5-nitro-2-furyl)buta-1,3-dienyl]quinoline; NSC 163031; Quinoline, 4,7-dichloro-2-[4-(5-nitro-2-furanyl)-1,3-butadien-1-yl]-; (E,E)-4,7-Dichloro-2-[4-(5-nitro-2-furyl)-1,3-butadienyl]quinoline
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Quality Control

Our 4,7-Dichloro-2-[(1E,3E)-4-(5-Nitro-2-Furyl)Buta-1,3-Dienyl]Quinoline is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for comprehensive characterization and purity verification. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your research and development documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance Yellow to orange crystalline powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 1.0%
Total Impurities (HPLC) ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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