Description

(7S,8R)-3',4',6,8-Tetrahydro-6'-Methoxy-2'-Methylspiro[7H-Indeno[4,5-D]-1,3-Dioxole-7,1'(2'H)-Isoquinoline]-7',8-Diol Diacetate is a high-purity, complex organic compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or reference standard for the development of novel therapeutic agents, particularly in the field of central nervous system (CNS) and analgesic drug discovery. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex alkaloid-derived molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex alkaloid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing to ensure product purity and identity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop new drug candidates with potential analgesic or neuroactive properties.
• Process Chemistry Development: Serves as a benchmark compound for optimizing synthetic routes, scaling up production, and improving yield in fine chemical synthesis.
• Academic Research: Utilized in university and institutional labs for studying the chemistry, pharmacology, and metabolism of spirocyclic and isoquinoline alkaloids.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value compounds for preclinical and clinical trials.

Basic Information

Product Name	(7S,8R)-3',4',6,8-Tetrahydro-6'-Methoxy-2'-Methylspiro[7H-Indeno[4,5-D]-1,3-Dioxole-7,1'(2'H)-Isoquinoline]-7',8-Diol Diacetate
CAS No.	30833-09-1
Molecular Formula	C24H25NO7
Molecular Weight	439.46 g/mol
Synonyms	7',8-Diacetoxy-6'-methoxy-2'-methylspiro[1,3-dioxolane-2,7'-3,4-dihydroisoquinoline]; Spiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinoline]-7',8-diol, 3',4',6,8-tetrahydro-6'-methoxy-2'-methyl-, diacetate, (7S,8R)-; O6',O7'-Diacetyl-6'-O-methylthevinone; Diacetyl-6-O-methylthevinone; Thevinone diacetate derivative
EINECS	Contact for details

Quality Control

Our (7S,8R)-3',4',6,8-Tetrahydro-6'-Methoxy-2'-Methylspiro[7H-Indeno[4,5-D]-1,3-Dioxole-7,1'(2'H)-Isoquinoline]-7',8-Diol Diacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.