Description

3α-Methoxycyclobutanone CAS NO 30830-25-2 is a versatile, highly volatile organic building block characterized by its unique four-membered ring structure functionalized with a methoxy group. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its strained ring system, which offers valuable reactivity for constructing complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those containing cyclobutane rings.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers and polymers with specific optical or mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including ring-opening and functionalization reactions.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of complex odorants and flavor molecules.

Basic Information

Product Name	3α-Methoxycyclobutanone
CAS No.	30830-25-2
Molecular Formula	C5H8O2
Molecular Weight	100.12 g/mol
Synonyms	3-Methoxycyclobutanone; (±)-3-Methoxycyclobutanone; 3-Methoxycyclobutan-1-one; Cyclobutanone, 3-methoxy-; 3-Methoxy-cyclobutanone; Methoxycyclobutanone; 30830-25-2
EINECS	Contact for details

Quality Control

Our 3α-Methoxycyclobutanone is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place at a recommended temperature of 2-8°C. Keep the container tightly sealed when not in use to prevent evaporation and potential contamination. Store away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.