Description

(S)-(-)-1,2-Epoxybutane is a high-purity chiral epoxide, a crucial building block in asymmetric synthesis. Its single enantiomeric form is essential for producing optically active intermediates with high stereoselectivity, ensuring the efficacy and safety of final products. This compound is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and fine chemical producers developing advanced chiral molecules.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material for the production of enantiomerically pure active pharmaceutical ingredients (APIs), such as β-blockers and other cardiovascular drugs.
• Agrochemical Production: Used in the synthesis of chiral herbicides, fungicides, and pesticides where biological activity is enantiomer-specific.
• Fine Chemical and Specialty Polymer Manufacturing: Serves as a monomer or precursor for creating polymers with specific optical properties or for synthesizing complex natural products and fragrances.
• Asymmetric Catalysis Research: Employed as a standard substrate or reagent in academic and industrial research to develop and test new chiral catalysts and synthetic methodologies.
• Liquid Crystal and Advanced Material Development: Utilized in the synthesis of chiral dopants and components for liquid crystal displays (LCDs) and other advanced optical materials.

Basic Information

Product Name	(S)-(-)-1,2-Epoxybutane
CAS No.	30608-62-9
Molecular Formula	C4H8O
Molecular Weight	72.11 g/mol
Synonyms	(S)-1,2-Butylene Oxide; (S)-(-)-Butylene Oxide; (2S)-2-Ethyloxirane; (S)-1,2-Epoxybutane; (-)-1,2-Epoxybutane; (S)-Butane-1,2-oxide; (S)-1,2-Butene oxide; L-1,2-Epoxybutane
EINECS	Contact for details

Quality Control

Our (S)-(-)-1,2-Epoxybutane is manufactured under strict quality management systems. Each batch is characterized and tested to ensure high enantiomeric excess (ee) and chemical purity, meeting the stringent requirements for chiral synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) for identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat, sparks, and open flame. Due to its highly volatile nature, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) when not in use to prevent evaporation and moisture ingress. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.