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6-Deoxy-1-O,2-o-Isopropylidene-3-O,5-o-Bis(Methylsulfonyl)-α-D-Glucofuranose CAS NO 30595-47-2
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CAS No.:30595-47-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
6-Deoxy-1-O,2-o-Isopropylidene-3-O,5-o-Bis(Methylsulfonyl)-α-D-Glucofuranose is a key protected carbohydrate derivative and versatile chiral building block in advanced organic synthesis. This compound is specifically engineered to provide reactive sites for selective functionalization, making it a critical intermediate for the production of complex molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and other fine chemicals where precise stereochemistry is paramount.
Application
- Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of modified nucleosides and carbohydrate-based therapeutics.
- Antiviral Drug Research: Serves as a chiral scaffold for developing novel antiviral compounds, including potential protease inhibitors.
- Glycochemistry: Used in the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics for biological studies.
- Chemical Biology Probes: Acts as a building block for creating labeled or tagged sugar analogs to study biological processes.
- Asymmetric Synthesis: Provides a stereochemically defined template for constructing molecules with high enantiomeric purity.
- Process Chemistry: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
Basic Information
| Product Name | 6-Deoxy-1-O,2-o-Isopropylidene-3-O,5-o-Bis(Methylsulfonyl)-α-D-Glucofuranose |
| CAS No. | 30595-47-2 |
| Molecular Formula | C11H20O9S2 |
| Molecular Weight | 360.40 g/mol |
| Synonyms | 1,2-O-Isopropylidene-3,5-di-O-methanesulfonyl-6-deoxy-α-D-glucofuranose; 3,5-Bis-O-(methylsulfonyl)-1,2-O-isopropylidene-6-deoxy-α-D-glucofuranose; 6-Deoxy-1,2-O-isopropylidene-3,5-di-O-(methylsulfonyl)-α-D-glucofuranose; 1,2-O-Isopropylidene-3,5-di-O-mesyl-6-deoxy-α-D-glucofuranose; 3,5-Di-O-methanesulfonyl-1,2-O-isopropylidene-6-deoxy-α-D-glucofuranose; 3,5-Dimesyl-1,2-O-isopropylidene-6-deoxy-α-D-glucofuranose; α-D-Glucofuranose, 6-deoxy-1,2-O-(1-methylethylidene)-3,5-bis-O-(methylsulfonyl)- |
| EINECS | Contact for details |
Quality Control
Our production of 6-Deoxy-1-O,2-o-Isopropylidene-3-O,5-o-Bis(Methylsulfonyl)-α-D-Glucofuranose adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Specific Rotation | Contact for details |
| Residual Solvents (GC) | Meets ICH guidelines |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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