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α-n-Acetylgalactosaminyl-(1-3)-[α-Fucosyl-(1-2)]-β-Galactosyl-(1-4)-β-n-Acetylglucosaminyl-(1-3)-β-Galactosyl-(1-4)-Glucose CAS NO 30461-82-6
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CAS No.:30461-82-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
α-n-Acetylgalactosaminyl-(1-3)-[α-Fucosyl-(1-2)]-β-Galactosyl-(1-4)-β-n-Acetylglucosaminyl-(1-3)-β-Galactosyl-(1-4)-Glucose is a complex, defined oligosaccharide of significant interest in advanced biochemical research and development. This compound serves as a critical high-purity reference standard and synthetic intermediate for studying carbohydrate-protein interactions, cell signaling, and antigenic determinants. It is primarily utilized by pharmaceutical R&D teams, diagnostic developers, and academic research institutions focused on glycobiology, immunology, and the development of novel therapeutics and vaccines.
Application
- Biochemical Research Standard: Used as a high-purity reference compound for the study of glycosylation patterns, enzyme specificity (glycosyltransferases/glycosidases), and carbohydrate-mediated biological recognition.
- Glycoconjugate Synthesis: Acts as a key building block or precursor in the chemical and enzymatic synthesis of more complex glycoproteins, glycolipids, and neoglycoconjugates.
- Immunological Studies: Employed in research related to blood group antigens, host-pathogen interactions, and the development of carbohydrate-based vaccines and diagnostic reagents.
- Cell Biology & Diagnostics: Utilized in the development of assays and tools for probing cell surface receptors (lectins), cell adhesion processes, and biomarker discovery.
- Enzyme Substrate/Inhibitor: Serves as a specific substrate for characterizing the activity of glycosyltransferases or as an inhibitor in studies of carbohydrate-processing enzymes.
- Pharmaceutical Intermediate: Potential intermediate in the development of targeted therapeutic agents where specific carbohydrate motifs are essential for bioactivity.
Basic Information
| Item | Details |
|---|---|
| Product Name | α-n-Acetylgalactosaminyl-(1-3)-[α-Fucosyl-(1-2)]-β-Galactosyl-(1-4)-β-n-Acetylglucosaminyl-(1-3)-β-Galactosyl-(1-4)-Glucose |
| CAS No. | 30461-82-6 |
| Molecular Formula | C46H77NO35 |
| Molecular Weight | 1172.08 g/mol |
| Synonyms | Blood Group A Type 2 Hexasaccharide; A Type 2 Hexasaccharide; GalNAcα1-3(Fucα1-2)Galβ1-4GlcNAcβ1-3Galβ1-4Glc; A-Tetrasaccharide Type 2-Lactose; A-Tetrasaccharide-Lactose; A-Tetra-Lac; 30461-82-6 |
| EINECS | Contact for details |
Quality Control
This product is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Quality is verified using advanced analytical techniques including HPLC, NMR, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your regulatory and research documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the product to equilibrate to room temperature in a dry atmosphere before opening to prevent condensation and moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 5.0% |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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