Description

2-(4-Methylphenyl)-4,7-Dihydro-4,7-Methano-2H-Isoindole is a specialized organic compound featuring a unique isoindole core fused with a norbornene-like methano bridge and a para-methylphenyl substituent. This complex, polycyclic structure makes it a valuable advanced intermediate for research and development in fine chemical synthesis. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel molecular architectures with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring complex, three-dimensional scaffolds.
• Agrochemical Research: Used in developing new active ingredients for crop protection, leveraging its rigid structure for potential insecticidal or herbicidal activity.
• Material Science Precursor: Serves as a monomer or functional additive in the research of specialty polymers, such as polyimides or liquid crystalline materials, due to its fused ring system.
• Organic Synthesis & Catalysis: Employed in academic and industrial research to explore new synthetic methodologies, including cycloaddition reactions and asymmetric catalysis.
• Ligand & Complexation Agent: The isoindole nitrogen can act as a donor site, making it a candidate for designing novel ligands in coordination chemistry and catalysis.

Basic Information

Product Name	2-(4-Methylphenyl)-4,7-Dihydro-4,7-Methano-2H-Isoindole
CAS No.	30451-33-3
Molecular Formula	C16H15N
Molecular Weight	221.30 g/mol
Synonyms	2-(p-Tolyl)-4,7-dihydro-4,7-methano-2H-isoindole; 2-(4-Methylphenyl)-4,7-dihydro-4,7-methanoisoindole; 4,7-Methano-2H-isoindole, 2-(4-methylphenyl)-4,7-dihydro-; 2-(4-Methylphenyl)-4,7-dihydro-4,7-epoxyisoindole (common misnomer); 2-p-Tolyl-4,7-dihydro-4,7-methano-2H-isoindole; N-(4-Methylphenyl)-4,7-dihydro-4,7-methanoisoindole; 30451-33-3
EINECS	Contact for details

Quality Control

Our 2-(4-Methylphenyl)-4,7-Dihydro-4,7-Methano-2H-Isoindole is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR), to ensure it meets exacting R&D standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). For long-term storage, consider storage under an inert atmosphere (e.g., nitrogen or argon) to minimize potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.