Description

(1α,3α,5α)-1,3,5-Trimethoxycyclohexane CAS NO 30363-89-4 is a high-purity, stereochemically defined cyclic ether derivative, valued for its role as a versatile building block and chiral auxiliary in advanced organic synthesis. Its significance lies in providing a rigid, oxygenated framework that is crucial for constructing complex molecular architectures, particularly in the pharmaceutical and fine chemical sectors. This compound is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty agrochemicals, and novel materials where precise stereochemistry and functional group compatibility are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those requiring a rigid, oxygenated cyclohexane scaffold.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for developing novel chiral ligands and catalysts used in enantioselective reactions.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, fragrances, and advanced polymer precursors where its methoxy groups offer specific reactivity.
• Agrochemical Research: Used in developing new generations of herbicides and pesticides with targeted biological activity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and material science research.

Basic Information

Product Name	(1α,3α,5α)-1,3,5-Trimethoxycyclohexane
CAS No.	30363-89-4
Molecular Formula	C9H18O3
Molecular Weight	174.24 g/mol
Synonyms	1,3,5-Trimethoxycyclohexane (all-cis); cis,cis-1,3,5-Trimethoxycyclohexane; (1alpha,3alpha,5alpha)-1,3,5-Trimethoxycyclohexane; Cyclohexane, 1,3,5-trimethoxy-, (1α,3α,5α)-; 1,3,5-Trimethoxy-cyclohexane, cis; All-cis-1,3,5-trimethoxycyclohexane; Hexahydro-1,3,5-trimethoxybenzene
EINECS	Contact for details

Quality Control

Our (1α,3α,5α)-1,3,5-Trimethoxycyclohexane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by GC or HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its sensitivity to oxidation, containers should be kept sealed and purged after each use to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee (all-cis isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.