Description

(4S,5S)-8α-[(S)-1,2-Dihydroxyethyl]-9β-Hydroxy-4-(4-Hydroxyphenyl)-1,7-Dioxaspiro[4.4]Nonane-2,6-Dione is a complex, high-purity spirocyclic compound of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate stereochemistry and functional groups make it a valuable chiral building block and a potential intermediate for novel active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and development laboratories in the pharmaceutical, agrochemical, and fine chemical sectors for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for complex target molecules.
• Asymmetric Synthesis: Utilized as a building block in stereoselective synthesis to construct molecules with specific three-dimensional configurations.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Reference Standard: Used as an analytical standard for quality control and method development in laboratories analyzing similar spirocyclic compounds.
• Fine Chemical Synthesis: Acts as a precursor for the synthesis of specialty chemicals, flavors, and fragrances requiring complex cyclic structures.
• Academic Research: Applied in university and institutional research exploring new synthetic methodologies and reaction mechanisms.

Basic Information

Product Name	(4S,5S)-8α-[(S)-1,2-Dihydroxyethyl]-9β-Hydroxy-4-(4-Hydroxyphenyl)-1,7-Dioxaspiro[4.4]Nonane-2,6-Dione
CAS No.	30358-74-8
Molecular Formula	C17H20O8
Molecular Weight	352.34 g/mol
Synonyms	1,7-Dioxaspiro[4.4]nonane-2,6-dione, 8α-[(1S)-1,2-dihydroxyethyl]-9β-hydroxy-4-(4-hydroxyphenyl)-, (4S,5S,8αS,9βS)-; 8α-[(1S)-1,2-Dihydroxyethyl]-9β-hydroxy-4-(4-hydroxyphenyl)-1,7-dioxaspiro[4.4]nonane-2,6-dione; Spirocyclic Dihydroxyethyl Hydroxyphenyl Dioxaspiro Dione; CAS 30358-74-8
EINECS	Contact for details

Quality Control

Our (4S,5S)-8α-[(S)-1,2-Dihydroxyethyl]-9β-Hydroxy-4-(4-Hydroxyphenyl)-1,7-Dioxaspiro[4.4]Nonane-2,6-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.