Description

5-Bromo-2-Nitrobenzofuran is a specialized heterocyclic aromatic compound that serves as a crucial synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both bromo and nitro substituents on the benzofuran core, makes it a versatile building block for constructing complex molecular architectures. This high-purity intermediate is primarily utilized by research institutions and industrial R&D departments engaged in pharmaceutical development, agrochemical synthesis, and materials science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive sites for structural modification.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions to introduce the benzofuran scaffold into target molecules.
• Material Science: Serves as a monomer or precursor for the development of organic electronic materials, such as OLEDs and conductive polymers.
• Dye and Pigment Synthesis: Intermediate in the production of specialized dyes and pigments due to the chromophoric benzofuran system.
• Academic and Contract Research: Essential reagent for methodological studies and discovery chemistry within university and CRO laboratories.

Basic Information

Product Name	5-Bromo-2-Nitrobenzofuran
CAS No.	30335-67-2
Molecular Formula	C8H4BrNO3
Molecular Weight	242.03 g/mol
Synonyms	5-Bromo-2-nitro-1-benzofuran; 2-Nitro-5-bromobenzofuran; 1-Benzofuran, 5-bromo-2-nitro-; 5-Brom-2-nitrobenzofuran; 5-Bromo-2-nitro-benzo[b]furan; NSC 406906
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Nitrobenzofuran is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.