Description

1-Iodo-4-Nitrobenzene is a versatile halogenated nitroaromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and a nitro group, makes it a valuable precursor for creating complex molecules through cross-coupling and nucleophilic substitution reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring aryl-iodide motifs in Suzuki-Miyaura or other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents where the nitro and iodo groups allow for further functionalization.
• Liquid Crystal & OLED Material Production: Serves as a starting material for synthesizing advanced organic electronic materials and liquid crystal compounds.
• Dye & Pigment Manufacturing: Intermediate in the production of complex azo dyes and other colored organic compounds.
• Academic & Industrial R&D: A valuable reagent for method development in organic chemistry, particularly in studies involving halogen exchange and aromatic substitution.
• Polymer Modification: Used to introduce functional aromatic groups into polymer chains to alter physical or chemical properties.

Basic Information

Product Name	1-Iodo-4-Nitrobenzene
CAS No.	30306-69-5
Molecular Formula	C6H4INO2
Molecular Weight	249.01 g/mol
Synonyms	4-Nitroiodobenzene; p-Iodonitrobenzene; 4-Iodonitrobenzene; p-Nitroiodobenzene; 1-Iodo-4-nitro-benzene; (4-Nitrophenyl)iodide; Nitrophenyl iodide
EINECS	250-136-5

Quality Control

Our 1-Iodo-4-Nitrobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation via FT-IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	Pale yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	171 - 174 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.