Description

(2R,8Aβ)-Decahydro-α,α,4Aα-Trimethylnaphthalene-2α-Methanol is a high-purity, stereochemically defined decalin derivative with a functionalized methanol side chain, serving as a critical chiral intermediate in advanced organic synthesis. Its rigid, fused-ring structure and defined stereochemistry make it invaluable for constructing complex molecular architectures with precise spatial orientation. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fragrance industries seeking to develop novel active ingredients with high stereoselectivity.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel therapeutic agents, particularly in steroid mimetics and complex natural product derivatives.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthesizing high-value, stereochemically pure odorants and flavor compounds with unique sensory profiles.
• Advanced Material Research: Employed as a monomer or modifying agent in the development of specialty polymers and liquid crystals.
• Catalyst & Ligand Development: Utilized as a scaffold for creating novel chiral ligands and organocatalysts for asymmetric synthesis.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological studies in synthetic organic chemistry.

Basic Information

Item	Details
Product Name	(2R,8Aβ)-Decahydro-α,α,4Aα-Trimethylnaphthalene-2α-Methanol
CAS No.	30254-86-5
Molecular Formula	C₁₄H₂₆O
Molecular Weight	210.36 g/mol
Synonyms	(2R,8aS)-Decahydro-α,α,4a-trimethyl-2-naphthalenemethanol; (2R,8aS)-2-Hydroxymethyl-1,1,4a-trimethyl-decahydronaphthalene; Ambrox; Ambroxide Precursor; (2R,8aS)-Ambroxol Intermediate; (2R,8aS)-Decahydro-2-hydroxy-1,1,4a-trimethylnaphthalene; (2R,8aS)-1,1,4a-Trimethyl-decahydro-2-naphthalenemethanol; (-)-Ambrox
EINECS	Contact for details

Quality Control

Our (2R,8Aβ)-Decahydro-α,α,4Aα-Trimethylnaphthalene-2α-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC and GC, to ensure high stereochemical and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (2R,8aS)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.