Description

3-(o-Hydroxyphenyl)Quinazolin-4(3H)-One is a specialized heterocyclic organic compound that serves as a key synthetic intermediate and a versatile pharmacophore in advanced chemical synthesis. Its unique quinazolinone core fused with a phenolic moiety makes it a valuable building block for developing molecules with targeted biological activity. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive scaffold.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a core structure for developing electron-transporting or host materials in optoelectronic applications.
• Coordination Chemistry & Ligand Synthesis: The phenolic and nitrogen donor atoms make it a useful chelating ligand for constructing metal-organic complexes.
• Biochemical Probe Development: Employed in medicinal chemistry to create fluorescent probes or activity-based protein profiling agents.
• Academic & Industrial R&D: A fundamental reagent for exploring new organic reactions and synthesizing complex heterocyclic libraries.

Basic Information

Product Name	3-(o-Hydroxyphenyl)Quinazolin-4(3H)-One
CAS No.	3977-51-3
Molecular Formula	C₁₄H₁₀N₂O₂
Molecular Weight	238.24 g/mol
Synonyms	2-(4-Oxo-3,4-dihydroquinazolin-3-yl)phenol; 3-(2-Hydroxyphenyl)-4(3H)-quinazolinone; 3-(2-Hydroxyphenyl)quinazolin-4-one; NSC 403697; 4(3H)-Quinazolinone, 3-(2-hydroxyphenyl)-; Phenol, 2-(4-oxo-3,4-dihydro-3-quinazolinyl)-
EINECS	Contact for details

Quality Control

Our 3-(o-Hydroxyphenyl)Quinazolin-4(3H)-One is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. For custom synthesis or specific purity requirements (e.g., >98%, >99%), please contact our technical team to discuss your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.