Description

(2S)-2-(2,4-Dinitrophenylamino)-4-(Methylthio)Butyric Acid is a specialized chiral amino acid derivative characterized by its dinitrophenyl (DNP) protecting group and a methylthio side chain. This compound matters as a key synthetic intermediate and research chemical, valued for its role in peptide chemistry and biochemical studies where the DNP group is utilized for specific labeling or protection strategies. It is needed by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing novel bioactive molecules, peptide-based therapeutics, and advanced analytical standards.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in proteomics and enzyme studies, where the 2,4-dinitrophenyl (DNP) moiety acts as a chromophore or a specific label for detection and analysis.
• Peptide Synthesis: Functions as a protected or modified amino acid derivative in solid-phase and solution-phase peptide synthesis to introduce specific functional groups.
• Analytical Standard: Employed as a high-purity reference standard in HPLC, LC-MS, and other chromatographic methods for method development and quality control.
• Organic Synthesis: Acts as a versatile chiral synthon for constructing more complex sulfur-containing organic molecules and heterocycles.
• Material Science Research: Investigated for potential use in the development of novel functional materials and polymers with specific optical or electronic properties.

Basic Information

Product Name	(2S)-2-(2,4-Dinitrophenylamino)-4-(Methylthio)Butyric Acid
CAS No.	3950-28-5
Molecular Formula	C11H13N3O6S
Molecular Weight	315.30 g/mol
Synonyms	DNP-Met-OH; (S)-2-((2,4-Dinitrophenyl)amino)-4-(methylthio)butanoic acid; L-2,4-Dinitrophenylmethionine; N-(2,4-Dinitrophenyl)-L-methionine; 4-(Methylthio)-2-[(2,4-dinitrophenyl)amino]butanoic acid; 3950-28-5; Butanoic acid, 2-[(2,4-dinitrophenyl)amino]-4-(methylthio)-, (2S)-
EINECS	Contact for details

Quality Control

Our (2S)-2-(2,4-Dinitrophenylamino)-4-(Methylthio)Butyric Acid undergoes rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system supports production under GMP-like conditions for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct or strong artificial light.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.