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Methyl 2-Acetamido-2-Deoxy-β-D-Glucopyranoside CAS NO 3946-01-8


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CAS No.:3946-01-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 2-Acetamido-2-Deoxy-β-D-Glucopyranoside is a key glycoside derivative of N-acetylglucosamine, serving as a fundamental building block in carbohydrate chemistry and glycobiology research. This compound is essential for the synthesis of complex oligosaccharides, glycoconjugates, and as a standard for analytical studies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, enzyme substrate studies, and the development of novel biomaterials.

Application

  • Glycobiology Research: Critical substrate and intermediate for studying glycosyltransferases, glycosidases, and other carbohydrate-active enzymes.
  • Pharmaceutical Development: Used as a precursor in the synthesis of glycosylated drug candidates, including antiviral and anti-cancer agents.
  • Oligosaccharide Synthesis: Serves as a versatile starting material and glycosyl acceptor/donor for constructing complex carbohydrate chains.
  • Biochemical Standards: Employed as a high-purity reference standard in HPLC, LC-MS, and NMR analysis for method development and quality control.
  • Glycoconjugate Production: Integral to the chemical and enzymatic preparation of glycoproteins, glycolipids, and neoglycoconjugates for diagnostic and therapeutic applications.
  • Enzyme Inhibitor Studies: Useful in the design and evaluation of inhibitors targeting carbohydrate-processing enzymes.

Basic Information

Product Name Methyl 2-Acetamido-2-Deoxy-β-D-Glucopyranoside
CAS No. 3946-01-8
Molecular Formula C9H17NO6
Molecular Weight 235.23 g/mol
Synonyms Methyl N-Acetyl-β-D-glucosaminide; Methyl 2-Acetamido-2-deoxy-β-D-glucopyranoside; N-Acetyl-β-D-glucosamine methyl glycoside; β-Methyl N-acetylglucosaminide; 2-Acetamido-2-deoxy-β-D-glucopyranoside methyl ether; GlcNAc-β-OMe; 1-O-Methyl-2-acetamido-2-deoxy-β-D-glucopyranose; N-Acetyl-β-methyl-D-glucosaminide
EINECS 223-531-1

Quality Control

Our Methyl 2-Acetamido-2-Deoxy-β-D-Glucopyranoside is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Specific Rotation [α]20/D -30° to -35° (c=1 in H2O)
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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