Description

N-(3-Chloro-2-Hydroxypropyl)Acetamide is a versatile bifunctional organic intermediate featuring both a reactive chloro and a hydroxyl group on a short alkyl chain. This compound matters for its utility as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and specialty chemical manufacturing. Industries that require fine chemical synthesis, such as pharmaceuticals, agrochemicals, and polymer modification, are the primary users of this material.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a chlorohydrin or amino alcohol moiety.
• Agrochemical Synthesis: Serves as a precursor for herbicides, fungicides, and plant growth regulators.
• Polymer Modification: Acts as a cross-linking agent or a monomer for specialty resins and coatings.
• Bioconjugation Reagent: Utilized in biochemical research for modifying proteins or other biomolecules.
• Surfactant and Detergent Industry: A potential intermediate for the production of amphoteric or cationic surfactants.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing heterocycles and other complex organic structures.

Basic Information

Product Name	N-(3-Chloro-2-Hydroxypropyl)Acetamide
CAS No.	3920-11-4
Molecular Formula	C5H10ClNO2
Molecular Weight	151.59 g/mol
Synonyms	1-Acetamido-3-chloro-2-propanol; 3-Chloro-2-hydroxypropylacetamide; N-(3-Chloro-2-hydroxypropyl)acetamide; Acetamide, N-(3-chloro-2-hydroxypropyl)-; 2-Hydroxy-3-chloropropylacetamide; 3-Chloro-2-hydroxy-1-propylacetamide; Chlorohydroxypropylacetamide; Glycidylacetamide hydrochloride (related)
EINECS	223-485-4

Quality Control

Our N-(3-Chloro-2-Hydroxypropyl)Acetamide is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics. We support compliance with global regulatory frameworks including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The product may be hygroscopic; ensure containers are sealed after use to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.