Description

(7As,8S)-6,7,7A,8-Tetrahydro-4-Methoxy-7-Methyl-5H-Benzo[G]-1,3-Benzodioxolo[6,5,4-De]Quinolin-8-Ol is a complex, chiral alkaloid derivative with a fused polycyclic structure, making it a valuable intermediate in advanced organic synthesis. Its precise stereochemistry and functional groups are critical for applications requiring high specificity and purity, such as pharmaceutical research and development. This compound is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for use as a key building block in the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate receptor interactions and enzyme inhibition.
• Asymmetric Synthesis: Employed as a starting material or catalyst ligand in stereoselective chemical reactions to create other complex chiral molecules.
• Agrochemical Development: Acts as a key intermediate in the research and development of new, high-specificity pesticides and herbicides.
• Academic Research: Utilized in university and institutional laboratories for methodological development in organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	(7As,8S)-6,7,7A,8-Tetrahydro-4-Methoxy-7-Methyl-5H-Benzo[G]-1,3-Benzodioxolo[6,5,4-De]Quinolin-8-Ol
CAS No.	3912-56-9
Molecular Formula	C20H21NO5
Molecular Weight	355.39 g/mol
Synonyms	Berberrubine; 9-Demethylberberine; 9-O-Demethylberberine; NSC 11905; 9-Desmethylberberine; 9-Hydroxy-10-methoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium; (7as,8S)-6,7,7a,8-Tetrahydro-4-methoxy-7-methyl-5H-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-ij]isoquinolino[2,1-b]isoquinolin-8-ol
EINECS	Contact for details

Quality Control

Our (7As,8S)-6,7,7A,8-Tetrahydro-4-Methoxy-7-Methyl-5H-Benzo[G]-1,3-Benzodioxolo[6,5,4-De]Quinolin-8-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.