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(R)-(+)-1-(1-Naphthyl)Ethylamine CAS NO 3886-70-2
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CAS No.:3886-70-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R)-(+)-1-(1-Naphthyl)Ethylamine is a high-purity chiral amine building block of significant importance in asymmetric synthesis. Its value lies in its role as a versatile resolving agent and chiral auxiliary for the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high optical purity intermediates.
Application
- Chiral Resolution Agent: Widely used for the separation of racemic mixtures of carboxylic acids and other acidic compounds.
- Asymmetric Synthesis: Serves as a key chiral auxiliary or ligand in catalytic asymmetric reactions, including hydrogenations and alkylations.
- Pharmaceutical Intermediates: Critical building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific (R)-configuration.
- Agrochemical Development: Used in the research and production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
- Catalyst Preparation: Employed in the synthesis of chiral catalysts and metal-organic frameworks (MOFs) for stereoselective processes.
- Analytical Chemistry: Utilized as a chiral selector or derivatizing agent in chromatographic methods like HPLC for enantiomeric purity analysis.
Basic Information
| Product Name | (R)-(+)-1-(1-Naphthyl)Ethylamine |
| CAS No. | 3886-70-2 |
| Molecular Formula | C₁₂H₁₃N |
| Molecular Weight | 171.24 g/mol |
| Synonyms | (R)-(+)-1-(1-Naphthyl)ethylamine; (R)-1-(Naphthalen-1-yl)ethan-1-amine; (R)-1-(1-Naphthyl)ethylamine; (+)-(R)-1-(1-Naphthyl)ethylamine; (R)-1-(1-Naphthalenyl)ethylamine; (R)-α-Methyl-1-naphthalenemethylamine; D-NEA; (R)-NEA |
| EINECS | 223-418-4 |
Quality Control
Our (R)-(+)-1-(1-Naphthyl)Ethylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high optical purity. Each lot is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to meet the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) detailing purity, specific rotation, and impurity profiles are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% ee |
| Specific Rotation [α]²⁰D | +40.0° to +44.0° (c=1 in Ethanol) |
| Melting Point | 48°C - 52°C |
| Loss on Drying | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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