Description

3-(Trifluoromethylthio)Nitrobenzene is a versatile aromatic nitro compound distinguished by its trifluoromethylthio functional group. This unique structure makes it a valuable advanced intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the bioisosteric trifluoromethylthio moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the nitro and sulfur-containing groups contribute to biological activity.
• Organic Synthesis & Material Science: Serves as a precursor for ligands, catalysts, and specialty polymers, enabling the introduction of fluorine and sulfur atoms into complex structures.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and colorants, leveraging its nitro-aromatic core.

Basic Information

Product Name	3-(Trifluoromethylthio)Nitrobenzene
CAS No.	3849-68-1
Molecular Formula	C7H4F3NO2S
Molecular Weight	223.17 g/mol
Synonyms	1-Nitro-3-(trifluoromethylthio)benzene; 3-Nitrobenzenetrifluoromethyl sulfide; m-(Trifluoromethylthio)nitrobenzene; α,α,α-Trifluoro-m-nitrothioanisole; Benzene, 1-nitro-3-[(trifluoromethyl)thio]-; NSC 404087; 3-Trifluoromethylsulfanylnitrobenzene
EINECS	223-356-5

Quality Control

Our 3-(Trifluoromethylthio)Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.