Description

1-Ethyl-6-Fluoro-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid is a high-purity, versatile quinoline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of fluoroquinolone antibiotics and other therapeutic agents.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Chemical Synthesis: Serves as a versatile scaffold for constructing complex heterocyclic compounds in organic chemistry laboratories.
• API Manufacturing: Employed in the multi-step synthesis of active pharmaceutical ingredients under controlled GMP environments.
• Biochemical Research: Utilized as a reference standard or probe in biochemical assays to study enzyme interactions.

Basic Information

Product Name	1-Ethyl-6-Fluoro-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid
CAS No.	3832-97-1
Molecular Formula	C₁₂H₁₀FNO₃
Molecular Weight	235.21 g/mol
Synonyms	6-Fluoro-1-ethyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid; 6-Fluoro-1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; Ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (common misnomer); 3-Quinolinecarboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-4-oxo-; ENX-1; A fluoroquinolone precursor.
EINECS	223-322-8

Quality Control

Our 1-Ethyl-6-Fluoro-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.