Description

1,2-Dihydro-4-(131I)Iodo-1,5-Dimethyl-2-Phenyl-3H-Pyrazol-3-One CAS NO 3791-63-7 is a specialized iodinated pyrazolone derivative, critically important as a precursor or intermediate in the synthesis of radiolabeled compounds for diagnostic and research applications. Its core value lies in enabling the precise incorporation of iodine-131, a γ-emitting radioisotope, into target molecules for medical imaging and therapeutic studies. This compound is essential for pharmaceutical R&D laboratories, radiopharmaceutical manufacturers, and academic institutions focused on developing novel tracers for nuclear medicine, particularly in oncology and neurology.

Application

• Radiopharmaceutical Precursor: Key intermediate for synthesizing iodine-131 labeled diagnostic agents and therapeutic radiopharmaceuticals.
• Medical Imaging Research: Used in the development of novel SPECT (Single-Photon Emission Computed Tomography) tracers for cancer detection and metabolic studies.
• Theragnostic Development: Serves as a building block for compounds used in combined diagnostic and therapeutic (theragnostic) approaches.
• Biomolecule Radiolabeling: Facilitates the iodination of peptides, antibodies, or small molecules for biodistribution and pharmacokinetic research.
• Chemical Biology Probes: Enables the creation of radiolabeled probes for studying enzyme activity, receptor binding, and cellular pathways.
• Reference Standard: Acts as a critical reference material for quality control and analytical method development in radiochemistry.

Basic Information

Item	Details
Product Name	1,2-Dihydro-4-(131I)Iodo-1,5-Dimethyl-2-Phenyl-3H-Pyrazol-3-One
CAS No.	3791-63-7
Molecular Formula	C11H11IN2O * (131I)
Molecular Weight	Contact for details
Synonyms	4-(131I)Iodoantipyrine; 131I-Iodoantipyrine; [131I]Iodoantipyrine; Iodoantipyrine (131I); 1,5-Dimethyl-2-phenyl-4-(131I)iodo-3-pyrazolone; 4-Iodoantipyrine-131I; Antipyrine, 4-iodo-, labeled with iodine-131; Radioiodinated Antipyrine
EINECS	Contact for details

Quality Control

Every batch of our 1,2-Dihydro-4-(131I)Iodo-1,5-Dimethyl-2-Phenyl-3H-Pyrazol-3-One is manufactured and controlled under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and specific activity, meeting the stringent requirements for radiopharmaceutical intermediates. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting critical parameters such as radiochemical purity, radionuclidic purity, and chemical purity.

Storage

Preserve in a tightly closed container, protected from light. Due to its radioactive nature and sensitivity, this material should be stored in appropriate shielded containment as per local radiation safety regulations. Store at controlled room temperature (15-25°C) or as specified on the label. Handle and dispose of in accordance with all applicable federal, state, and local radiation protection guidelines.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 95%
Radionuclidic Purity (Gamma Spectrometry)	≥ 99%
Specific Activity	Contact for details
Chemical Purity (HPLC)	≥ 98%
Solubility	Soluble in ethanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.