Description

3-Iodobenzylamine Hydrochloride CAS NO 3718-88-5 is a halogenated benzylamine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic scaffold with both an amine handle and an iodine atom suitable for further cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in medicinal chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides that require halogenated aromatic structures.
• Chemical Synthesis Reagent: The iodine substituent makes it a prime candidate for further functionalization via palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Material Science Research: Employed in the creation of organic electronic materials and advanced polymers.
• Bioconjugation and Probe Development: Useful for creating fluorescent probes or affinity labels in biochemical research due to its reactive amine group.

Basic Information

Item	Details
Product Name	3-Iodobenzylamine Hydrochloride
CAS No.	3718-88-5
Molecular Formula	C7H9IN·HCl
Molecular Weight	269.52 g/mol
Synonyms	(3-Iodophenyl)methanamine hydrochloride; 1-(3-Iodobenzyl)amine hydrochloride; 3-Iodo-α-toluidine hydrochloride; m-Iodobenzylamine HCl; 3-Iodobenzenemethanamine hydrochloride; Benzenemethanamine, 3-iodo-, hydrochloride; 3-Iodo-benzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Iodobenzylamine Hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.