Description

Chlorhexidine Hydrochloride is a potent cationic bisbiguanide salt widely recognized for its broad-spectrum antimicrobial efficacy. This compound is a critical active pharmaceutical ingredient (API) and disinfectant agent, valued for its persistent action against bacteria, fungi, and certain viruses. It is essential for manufacturers in the pharmaceutical, personal care, and veterinary sectors requiring a reliable antiseptic component. The global market for this product, CAS NO 3697-42-5, is driven by stringent hygiene standards across healthcare and consumer product industries.

Application

• Pharmaceutical Antiseptic: Primary active ingredient in surgical scrubs, hand sanitizers, and pre-operative skin disinfectants.
• Oral Care Products: Key component in mouthwashes, toothpastes, and gels for controlling plaque and gingivitis.
• Veterinary Medicine: Used in disinfectant solutions, wound care sprays, and teat dips for livestock.
• Medical Device Preservation: Incorporated into coatings and solutions for disinfecting catheters, implants, and other sterile supplies.
• Cosmetic Preservation: Serves as a preservative in creams, lotions, and other topical formulations to prevent microbial growth.
• Surface Disinfectants: Formulated into hard-surface cleaners and wipes for clinical and institutional environments.
• Ophthalmic Solutions: Used at low concentrations in contact lens cleaning and storage solutions.

Basic Information

Product Name	Chlorhexidine Hydrochloride
CAS No.	3697-42-5
Molecular Formula	C22H30Cl2N10 · 2HCl
Molecular Weight	578.4 g/mol
Synonyms	Chlorhexidine Dihydrochloride; 1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide] Dihydrochloride; N,N''-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide Dihydrochloride; Chlorhexidine HCl; Hibitane Dihydrochloride; PHMB Hydrochloride (related); CAS 3697-42-5; Biguanide, Chlorhexidine, Hydrochloride
EINECS	223-026-6

Quality Control

Our Chlorhexidine Hydrochloride is manufactured under a GMP-compliant quality management system, ensuring batch-to-batch consistency for critical applications. The product is tested against stringent in-house specifications, which may align with USP, EP, or BP monograph standards as required. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and formulation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to prevent caking and maintain stability.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (on dried basis)	98.0% - 102.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Microbial Enumeration Tests	Meets requirements for specified grade

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.