Description

Glucurono-1,4-Lactone Isonicotinoylhydrazone is a specialized organic compound formed by the condensation of D-glucurono-1,4-lactone with isonicotinoyl hydrazide. This compound is valued for its unique molecular structure, which combines carbohydrate and heterocyclic pharmacophore elements, making it a versatile intermediate in advanced chemical synthesis. It is primarily sought by research institutions and pharmaceutical development companies for the creation of novel chemical entities, particularly in medicinal chemistry and biochemical research.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and development of new therapeutic agents, particularly those targeting metabolic pathways.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate glucuronidation processes and related biochemical mechanisms.
• Medicinal Chemistry: Acts as a precursor for synthesizing novel hydrazone derivatives with potential biological activity for drug discovery programs.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Chemical Synthesis: Utilized in organic synthesis to introduce specific functional groups, leveraging its reactive hydrazone and lactone moieties.

Basic Information

Product Name	Glucurono-1,4-Lactone Isonicotinoylhydrazone
CAS No.	3691-74-5
Molecular Formula	C₁₃H₁₅N₃O₇
Molecular Weight	325.27 g/mol
Synonyms	D-Glucurono-1,4-lactone isonicotinoylhydrazone; Isonicotinoylhydrazone of D-Glucurono-1,4-lactone; Glucuronolactone isonicotinoylhydrazone; 4-Pyridinecarboxylic acid, [(3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxotetrahydro-2H-pyran-2-yl]methylene]hydrazide; Isonicotinic acid (D-glucuronolactonylidene)hydrazide
EINECS	Contact for details

Quality Control

Our Glucurono-1,4-Lactone Isonicotinoylhydrazone is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.