Description

(R*,R*)-(±)-2-Amino-1-(p-Nitrophenyl)Propane-1,3-Diol is a chiral amino diol derivative featuring a p-nitrophenyl group, serving as a versatile and critical building block in advanced organic synthesis. This compound matters because it provides a rigid, functionalized scaffold essential for constructing complex molecules with specific stereochemistry, which is paramount in developing active pharmaceutical ingredients (APIs) and specialty chemicals. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications such as chiral ligand synthesis, resolution agents, and the preparation of key intermediates for drug discovery programs.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key precursor for the development of enantiomerically pure APIs, particularly in classes requiring amino diol motifs.
• Ligand for Asymmetric Catalysis: Used to synthesize chiral ligands for metal-catalyzed reactions, enabling high stereoselectivity in C-C and C-N bond formations.
• Building Block for Specialty Chemicals: Employed in the research and production of advanced materials, liquid crystals, and performance chemicals where specific molecular geometry is required.
• Resolution Agent: Utilized in the chiral resolution of racemic mixtures of acids or other compounds due to its ability to form diastereomeric salts.
• Agrochemical Intermediate: Serves as a starting material for synthesizing novel, biologically active compounds with potential herbicidal or insecticidal properties.
• Research & Development (R&D): A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and studying structure-activity relationships (SAR).

Basic Information

Product Name	(R*,R*)-(±)-2-Amino-1-(p-Nitrophenyl)Propane-1,3-Diol
CAS No.	3689-55-2
Molecular Formula	C9H12N2O4
Molecular Weight	212.20 g/mol
Synonyms	DL-threo-1-(4-Nitrophenyl)-2-amino-1,3-propanediol; (±)-threo-1-p-Nitrophenyl-2-aminopropane-1,3-diol; Chloramphenicol Base Intermediate; 2-Amino-1-(4-nitrophenyl)-1,3-propanediol; 1-(4-Nitrophenyl)-2-amino-1,3-propanediol; threo-1-(p-Nitrophenyl)-2-amino-1,3-propanediol; AMPD; p-Nitrophenyl amino propanediol
EINECS	223-015-3

Quality Control

Our (R*,R*)-(±)-2-Amino-1-(p-Nitrophenyl)Propane-1,3-Diol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and consistent performance. Standard quality parameters include assay by titration, chiral purity by HPLC, and control of related substances. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (threo isomer)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.