Description

1,2-Diamino-1,2-dideoxy-D-mannitol is a specialized chiral diamine derivative of mannitol, a key building block in organic synthesis and pharmaceutical research. Its value lies in its unique stereochemistry and bifunctional amino groups, which enable its use as a versatile precursor for chiral ligands, catalysts, and complex molecular scaffolds. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors developing advanced active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral and anticancer research.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for synthesizing asymmetric catalysts used in enantioselective synthesis.
• Complexing Agent: Used in the development of chelating agents for metal ion sequestration and catalysis.
• Bioconjugation & Linker Chemistry: The primary amino groups facilitate its use as a spacer or linker in bioconjugation for diagnostic reagents and prodrugs.
• Polymer Modification: Employed to introduce functional amino groups into polymer backbones, enhancing material properties.
• Research & Development: A valuable tool compound in academic and industrial R&D for exploring new synthetic methodologies.

Basic Information

Product Name	1,2-Diamino-1,2-dideoxy-D-mannitol
CAS No.	3673-07-2
Molecular Formula	C6H16N2O4
Molecular Weight	180.20 g/mol
Synonyms	D-Mannitol, 1,2-diamino-1,2-dideoxy-; 1,2-Diamino-1,2-dideoxymannitol; (2R,3R,4R,5R)-2,3,4,5-Tetrahydroxyhexane-1,6-diamine; Hexitol, 1,2-diamino-1,2-dideoxy-, D-manno-; D-1,2-Diamino-1,2-dideoxymannitol; 1,2-Dideoxy-1,2-diamino-D-mannitol
EINECS	Contact for details

Quality Control

Our 1,2-Diamino-1,2-dideoxy-D-mannitol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) documenting identity, purity (HPLC), and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.