Description

D-Glucosamine 6-Phosphate is a key phosphorylated derivative of the amino sugar glucosamine, serving as a critical intermediate in the biosynthesis of amino sugars and glycoconjugates. This compound is essential for research and development in metabolic pathway studies, particularly those involving hexosamine biosynthesis and glycosylation processes. It is primarily utilized by biochemical researchers, pharmaceutical developers, and manufacturers of high-purity biochemical reagents for enzymatic assays, substrate studies, and the synthesis of more complex biomolecules.

Application

• Biochemical Research: Used as a substrate or intermediate in enzymatic studies, particularly for kinases and transferases involved in carbohydrate metabolism.
• Pharmaceutical Development: Serves as a key starting material or reference standard in the R&D of glycosylation-related therapeutics and metabolic modulators.
• Diagnostic Reagent Manufacturing: Employed in the formulation of assay kits for measuring enzyme activity in clinical and research settings.
• Glycobiology Studies: Essential for investigating the hexosamine biosynthesis pathway (HBP) and its role in cellular signaling and insulin resistance.
• Enzyme Characterization: Acts as a specific substrate for characterizing enzymes like glucosamine-6-phosphate N-acetyltransferase.
• Nutritional Science Research: Used in studies exploring the metabolic fate and biochemical roles of glucosamine derivatives.

Basic Information

Product Name	D-Glucosamine 6-Phosphate
CAS No.	3616-42-0
Molecular Formula	C6H14NO9P
Molecular Weight	299.15 g/mol
Synonyms	Glucosamine 6-Phosphate; D-Glucosamine-6-phosphate; 2-Amino-2-deoxy-D-glucose 6-phosphate; 6-O-Phosphono-D-glucosamine; (3R,4R,5S,6R)-3-Amino-6-(hydroxymethyl)oxane-2,4,5-triol 6-dihydrogen phosphate; 2-Amino-2-deoxy-D-glucopyranose 6-phosphate; G6P (Glucosamine); Amino sugar phosphate
EINECS	Contact for details

Quality Control

Our D-Glucosamine 6-Phosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (5% solution)	3.0 - 5.0
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.