Description

2-Acetamido-2-Deoxy-D-Mannose is a specialized amino sugar derivative, also known as N-Acetyl-D-mannosamine. This compound serves as a crucial chiral building block and biochemical precursor in advanced organic synthesis and life science research. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutics, glycoconjugates, and complex carbohydrates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sialic acid derivatives and neuraminic acid analogs, which are important for antiviral and anticancer drug development.
• Glycobiology Research: Essential substrate for studying glycosylation pathways, enzyme mechanisms (sialyltransferases), and cell surface recognition processes.
• Bioconjugate Chemistry: Used in the preparation of glycoproteins, glycolipids, and other biologically active conjugates for diagnostic and therapeutic applications.
• Carbohydrate Chemistry: Serves as a starting material for the synthesis of complex oligosaccharides and glycomimetics with tailored biological activities.
• Nutritional Science: Investigated for its role in metabolic pathways and as a potential supplement or functional food ingredient.
• Enzyme Substrate: Employed in enzymatic assays and for the production of sialic acid via biochemical conversion.

Basic Information

Item	Details
Product Name	2-Acetamido-2-Deoxy-D-Mannose
CAS No.	3615-17-6
Molecular Formula	C8H15NO6
Molecular Weight	221.21 g/mol
Synonyms	N-Acetyl-D-mannosamine; N-Acetylmannosamine; ManNAc; D-Mannosamine, N-acetyl-; 2-Acetamido-2-deoxy-D-mannopyranose; 2-(Acetylamino)-2-deoxy-D-mannose; Acetamidodeoxymannose
EINECS	222-806-1

Quality Control

Our 2-Acetamido-2-Deoxy-D-Mannose is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, optical rotation measurement, and residual solvent analysis to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Optical Rotation	+30.0° to +35.0° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.