Description

1-Bromo-2,6-Naphthyridin-3-Amine is a high-purity, functionalized naphthyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile halogenated amine intermediate, enabling the construction of complex molecular architectures with precision. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its halogen and amine functionality.
• Material Science: Building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Heterocyclic Chemistry: Core scaffold for further functionalization to create diverse libraries of naphthyridine-based compounds.

Basic Information

Product Name	1-Bromo-2,6-Naphthyridin-3-Amine
CAS No.	3611-11-8
Molecular Formula	C8H6BrN3
Molecular Weight	224.06 g/mol
Synonyms	3-Amino-1-bromo-2,6-naphthyridine; 1-Bromo-2,6-naphthyridin-3-ylamine; 2,6-Naphthyridine, 1-bromo-3-amino-; 1-Bromo-3-amino-2,6-naphthyridine; 3611-11-8; 3-Amino-1-bromonaphthyridine
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,6-Naphthyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.